Catalyst Molecule Model
Laboratory Assistance
             Unlock your model

Learn more about our chemistry


Efficient and Selective Formation of Macrocyclic Distributed Z Alkenes
The first broadly applicable set of protocols for efficient Z-selective formation of macrocyclic disubstituted alkenes through catalytic ring-closing metathesis (RCM) is described.
ChemViews, 23 January 2013


Z-Selective Olefin Metathesis Reactions Promoted by Tungsten Oxo Alkylidene Complexes
New homogeneous catalysts show highly promising activity and selectivity for a large variety of olefin metathesis reactions.
JACS, 8 January 2013


Molybdenum-Based Complexes with Two Aryloxides and a Pentafluoroimido Ligand
Catalysts for Efficient Z-Selective Synthesis of a Macrocyclic Trisubstituted Alkene by Ring-Closing Metathesis
Angewandte Chemie, 8 January 2013


Enol Ethers as Substrates for Efficient Z- and Enantioselective Ring-Opening/Cross-Metathesis Reactions Promoted by Stereogenic-at-Mo Complexes. Utility in Chemical Synthesis and Mechanistic Attributes
The first examples of catalytic enantioselective ring-opening/cross-metathesis (EROCM) reactions that involve enol ethers are reported. Catalytic EROCM of several oxa- and azabicycles, cyclobutenes and a cyclopropene with an alkyl- or aryl-substituted enol ether proceed readily in the presence of a stereogenic-at-Mo monopyrrolide-monoaryloxide.
J Am Chem Soc., 8 February 2012


Z-Selective Metathesis for Macrocycles
Tungsten catalysts dictate stereochemistry of double bond
C&EN, 7 November 2011 


Synthesis of macrocyclic natural products by catalyst-controlled stereoselective ring-closing metathesis
Nature, 3 November 2011 


Overcoming catalytic bias
Metathesis reactions can be used to make carbon-carbon double bonds - bar one isomeric class. By using new catalysts and balancing out the stabilities of intermediates in the reaction, the elusive isomers can be made.
Nature, 24 March 2011


Catalytic Z-selective olefin cross-metathesis for natural product synthesis
Here we report catalytic Z-selective cross-metathesis reactions of terminal enol ethers.
Nature, 24 March 2011


Synthesis of cis,syndiotactic ROMP Polymers Containing Alternating Enantiomers
JACS, 24 March 2011


Rigging Cross-Metathesis
Organic Synthesis: Molybdenum catalyst generates less stable Z olefin.
C&EN, 28 March 2011


Endo-Selective Enyne Ring-Closing Metathesis Promoted by Stereogenic-at-W Mono-Pyrrolide Complexes
The utility of W-alkylidene complexes for enyne ring-closing metathesis is demonstrated in a direct comparison with Mo-based analogs. Tungsten complexes lead to less alkyne oligomerization and higher levels of endo-selectivity and enantioselectivity.
Org Lett., 18 February 2011

XiMo partners with selected leading companies, providing access to its intellectual property and technical expertise, to solve important industrial chemistry problems.

XiMo was founded in 2010 by MIT Professor Richard Schrock and Boston College Professor Amir Hoveyda, along with a small group of other investors and co-founders.